Dexmedetomidine (Precedex) may cause which cardiovascular side effect?

Dexmedetomidine (Precedex) may cause which cardiovascular side effect?

• A. Hypertension
• B. Pulmonary edema
• C. Bradycardia
• D. Hypotension

Answer: (C)

Dexmedetomidine acts as an alpha-2 adrenergic agonist, which suppresses sympathetic outflow and reduces norepinephrine release. This central sympatholysis slows the heart and can lower blood pressure. The most characteristic cardiovascular effect is bradycardia, though hypotension can also occur from vasodilation. Hypertension and pulmonary edema are not typical adverse effects of this drug.

Dexmedetomidine acts as an alpha-2 adrenergic agonist, which suppresses sympathetic outflow and reduces norepinephrine release. This central sympatholysis slows the heart and can lower blood pressure. The most characteristic cardiovascular effect is bradycardia, though hypotension can also occur from vasodilation. Hypertension and pulmonary edema are not typical adverse effects of this drug.